Tell me your country, how you live, and I’ll tell you your risk of type 2 diabetes

Although it is fairly well known around us that the risk of type 2 diabetes is higher at lower income and cultural levels, in developing countries it is just the opposite

Type 2 diabetes is considered the fastest growing chronic disease in the world. The most IDF health expenditure up-to-date data from the World Diabetes Atlas (published regularly by the International Diabetes Federation, IDF) states that if by 2019 we have an estimated 463 million people with diabetes worldwide, by 2045 this figure is projected to be around 700 million. Thus, on average and within the global picture, it is estimated that one death from diabetes or its complications occurs every 8 seconds. The IDF estimates that the annual direct cost of diabetes worldwide is USD760 billion. By 2030 and 2045, these direct costs are projected to reach USD825 billion and USD845 billion, respectively. To this should be added the indirect cost (from premature death, disability and other diabetes-related complications), which is estimated to increase the direct cost by 35%.

Will it be my turn, will it be your turn?

The risk determinants of type 2 diabetes have typically focused on certain metabolic and physiological variables such as weight, waist circumference, blood pressure, etc. But if we take a step back, we can see that these target values can be related to lifestyles and genetics. It is not by chance that the IDF itself claimed in its 2015 report that proper lifestyle habits could prevent 70% of type 2 diabetes cases.

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But in many cases, it is useful to look at the extent to which the socio-economic status of a group can lead to predicting their risk of type 2 diabetes. The fact is that it is quite well established that, in general, those groups with a worse socioeconomic position have, at the same time, worse lifestyles: they smoke more, drink more, their dietary quality is worse and, again in general, they are more sedentary.

 

The 2017 paper entitled “Socio-economic status is associated with the prevalence of diabetes in the global picture” is as eloquent as its title. But it found that the relationship was inversely related to the level of development of the country concerned. That is, the prevalence of diabetes was directly correlated with the so-called ‘Human Development Index’ (or HDI*).  To summarize more graphically, in poor countries diabetes affects a greater proportion of higher income groups, and in rich countries the opposite is true for lower income groups.

 Diabetes repeats the story of obesity

A personal comment on these findings: Data highlighted, again, in this recent study by contrasting that, in China, having a higher income and a non-manual occupation was associated with a higher prevalence of type 2 diabetes, which was also predicted by the body mass index.

 

Not long ago, obesity was a feature associated with countries that were developing. But, unlike today, that obesity was more visible within the framework of a certain socio-economic status. It was a time when “corpulent” people (at that time they were not called “obese”) were represented in a caricatural way by that gentleman who in his maturity wore a hat, a Levite, a Havana cigar and a lady to match (she with long pearl necklaces).

However, nowadays, obesity (no longer called “corpulence”) is, in our environment, much more prevalent, more common, in those socially and economically depressed groups. Obesity has changed sides, as has diabetes.

This drift is to some extent associated with the concept of